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Statistical modelling and simulation engineer

Statistical modelling and simulation engineer for the development of long-term genetic improvement and conservation strategies

Deadline : 30/04/2025

Work environment, missions and activities

You will work in the BioForA Joint Research Unit (UMR) ('Integrated biology for the development of tree and forest diversity'), at the INRAE Val de Loire Centre in Orléans (France). This unit works on the development of forest genetic resources for sustainable wood production in a changing climate. The aim of the research is to elucidate the complexity of tree responses (in terms of wood formation, growth, reproduction or root development) to environmental variation and their relationship with aspects of wood production. To this end, the unit develops diverse approaches in physiology and functional genomics, quantitative and population genetics, and breeding and conservation methodology. The unit is involved in a number of projects and collaborations with government agencies for the management and production of forest reproductive material.

You will work in a H2020 collaborative research project currently running in our laboratory (OPTFOREST 2022-2027, https://www.optforests.eu/) and you will use simulations to compare different strategies for managing genetic diversity and genetic gain in the context of artificial selection that are operationally simple, quick to implement and inexpensive. These strategies will be based on different typologies of programmes corresponding to different species and their demogenetic, ecological, environmental and economic contexts. These typologies will be defined in collaboration with several European partners involved in the project, based on data and experience of their respective species and programmes. These strategies will be compared with a reference strategy based on optimal management of diversity and genetic gain for maximum efficiency in the short and long term. You will use the simulation tools and codes already available in our team (scripts using AlphaSimR and MoBPS), which you will be able to improve with new developments. These tools use virtual genomes with a finite number of loci and a set of hypotheses about the genetic architectures underlying the traits of interest. All data generation and processing will be carried out within a methodological framework that is reproducible, versioned and traceable at every stage. You will work in close collaboration with the scientists behind these typologies and with our bioinformatician on all aspects related to the reproducibility of the protocols. The results of this simulation and application work will be the subject of several scientific publications.

The proposed duration is 12 months and the starting date could be 1 July, subject to administrative procedures.

Working in Orléans (45, Loiret), mainly with computer workstations. Easy access to the laboratory by public transport (tramway and bus). Professional travel in France and Europe for meetings and workshops.

See also

Voir l'offre OT-25689 sur INRAE Jobs